Prepared by: Dr Mohd Zulkifli Bin Mohamad Zahir
Supervisor: Dr.Rizah Mazzuin Razali
Current posting: HKL
Case Scenario
73 y.o Mr.AS Malay Male
Underlying
DM
HPT
RIght Lacunar Infarct with residual mild Left Hemiparesis
IHD– 3 vessels disease done PCI
Meds
T Diamicron MR 30mg OD
T Amlodipine 5mg OD
T Cardiprin 100mg OD
T Atorvastatin 20mg ON
Premorbid ADLs and social background
1. iADLs
Still working as a kindergarten operator
Able to drive his car from KL– Penang by himself to manage his company
Meds, finances – managing these by himself
2. bADLs
Independent for bathing, dressing, personal hygiene, toilet, mobility, transfer, feeding
3. Social history
Lives with wife in a landed house–bungalow type, single storey
Has 3 children
Denies cigarette smoking/alcohol consumptions
Case History
Initially admitted for 5 days with Right Frontotemporoparietal lobe bleed and fall
Fell in the bathroom – event unwitnessed
Developed dysphagia, worsening left sided hemiplegia, treated conservatively
Upon discharged, patient had become dependent in all care
Initial CT Brain Report : Right frontotemporal parietal bleed
No expansion of bleed upon repeated CT scans
Cardiprin discontinued upon discharge
Case History
Readmitted to hospital 1 week post discharge
Presented with productive cough, fever and hypoactive delirium
Vital signs upon arrival
• BP : 140/70, HR 85, Temperature : 38.1, SpO2 97% under Room Air
No new neurological deficits, power 0/5 over Left Upper and Lower Limbs
Treated as Hospital Acquired Pneumonia
Completed 1 week of IV Tazocin 4.5g QID
Blood C&S : no growth
Repeated CT Brain at 2/52 post ICH event :
• Recent right MCA territory infarct with haemorrhagic transformation
CECT and CTA Brain at 4/52 post event :
• Right cerebral hemisphere rim enhancing lesions associated with gyriform enhancement, represent post infarct
• Residual Right temporal intraparenchymal haemorrhage
Case Progress
Plain CT Brain at 6/52 post event
• Residual haemorrhage at medial aspect of Right temporal lobe, reducing in size, measuring 0.4 x 0.6cm ( previously 0.5cm x 1.0cm)
• No new acute intraparenchymal haemorrhage
• Right MCA territory infarct with haemorrhagic transformation
Patient was subsequently transferred to Hospital Rehabilitasi Cheras for further period of rehabilitation
Medications list upon transfer
Syp lactulose 15 mls tds
Tab Calcium Carbonate 500 mg bd
Tab Calcitriol 0.25mcg od
Tab Bisoprolol 1.25mg OD
Tab Linagliptin 5mg OD
Tab Atorvastatin 20mg ON
Investigations
Investigations
ECG
Investigations
Echo
Ejection Fraction 40%, anteroseptal and inferior posterior hypokinesia
Normal LA size
No thrombus
Physiotherapist Assessment
Elderly Mobility Scale : 2/20 -> 4/20 -> 6/20
Bed mobility - independent rolling side to side
Sitting up : mod to max assist
Transfer : mod assist -> stand transfer with consistent cue
Sit to stand : pull to stand with mod assist -> push to stand using quadripod
Sitting balance – good for both static and dynamic
Standing balance - Static : fair, Dynamic : poor
Ambulation - Quadripode, need constant verbal cue
Occupational Therapist Assessment
Upon transfer to HRC (3 weeks post ICB event)
Modified Barthel Index (MBI) :27/100
Required maximal assistance for bADL
MMSE : 27/30
1st week rehab
MBI : 32/100
Maximal assistance for bADL
• Improvement in dressing, now requiring moderate assistance
• PU/BO – in diapers but able to indicate
2nd week rehab
MBI : 37/100
Improvement in ambulation – with quadripode
Speech Therapist Assessment
Meal observation done – no issue, some oral residue, requiring multiple swallow. Thus, need to remind patient
Speech: ok but poor respiration and prosody(intonation)
FEES : soft, moist diet and thin liquid with spoon
Points to ponder
The above figure is an image of his plain CT Brain at 2/52 post haemorrhagic event What is/are your differentials based on the image?
Based on the MDT assessment, outline the geriatric issues for the above case.
What are the risk factors for future fall in this patient’s case?
How do you mitigate the risk of a future CVA event?
What is/are the best approach for deciding to anticoagulate this patient?
CT shows hyperdense area with bleeding into the lesion suggestive of infarct with bleed or bleeding into a glioma. MRI may help.
Before anticoagulation, the risk and benefits need to be considered and this needs to be discussed with the family. The risk of falls is high due to stroke, diabetes and medications (OHG). OT, PT and nutrition support should be continued and attempts must be made to avoid hypoglycaemia and postural hypotension.
Sarath Lekamwasam
hyperdensity represents intraparenchymal bleed with surrounding cerebral oedema and midline shift; need to differentiate cytotoxic oedema with vasogenic oedema caused by SOL (tumour/abscess)
a. Cardioembolic stroke (AF/flutter) R MCA infarct with hemorrhagic transformation
b. possible thyrotoxic cardiomyopathy (HFmrEF) ddx ischemic
c. Deconditioning
d. Hypoactive delirium due to infection/recent stroke, post stroke cognitive impairment
e. Recent fall
3. stroke, cognitive impairment, sarcopenia, (postural hypotension not mentioned)
4. SPAF using DOAC after resolution of bleed, good glycemic and BP control
5. HASBLED 3- ensure good BP control while avoiding postural hypotension, ongoing outpatient rehab to mitigate falls risk (PT), close supervision while ambulating, home fall hazard assessment (OT), sensible footwear, shared decision making with caregiver re: decision for DOAC
1.CT brain got midline shift and looks like fingerlike projection like think need to rule out brain tumor/ vasogenic edema
1.MCA infarct with hemorrhagic transformation likely due to paroxysmal Af secondary to hyperthyroidism (cardioembolic)
with left hemiparesis n dysphasia
2.heart failure reduce EF due to ischemic cardiomyopathy
CHADSVAS- 6- need to discuss with him n family regarding Choice of anticoag risk of bleeding vs benefit recurrent stroke( rpt scan make sure no bleeding prior starting)-individualised and timing of anticoag NOAC therapy- rather than follow diener law (https://www.ahajournals.org/doi/10.1161/STROKEAHA.121.036695)
treat the hyperthyroidism
optimise pillars of heart failure treatment
nutrition( dietician) and regular PT OT
Education on diet modication and technique (speech)- reduce risk of aspiration pneumonia
Monitor emotion- depression/ agitation( affect Frontal/…